Are you suffering from leaky gut? Listen to this episode to find out
Leaky gut after gastric bypass and gastric sleeve surgery is more common than you might think. In this episode of the Gastric Health Show, we discuss what leaky gut really is and things you can do to fix it.
Your intestinal tract is more than just your “guts”
Your GI tract consists of an enormous surface area that is optimized to absorb nutrients, water, and electrolytes from food. At the same time, it provides a tight barrier that protects you from both harmful substances and compounds.
In short, when you have leaky gut it equals dysfuctional intestinal permeability.
Leaky gut is associated with various diseases and disorders
The following issues are all associated or caused by leaky gut (dysfunctional intestinal barrier).
- Gut infections
- Inflammatory bowel disease
- IBS (irritable bowel syndrome)
- Celiac disease
- Non-celiac gluten sensitivity
- Food allergies
In the case of obesity, it is classically associated with metabolic alterations related to glucose homeostasis such as glucose intolerance, type 2 diabetes, insulin resistance, and cardiovascular risk factors (HTN, dyslipidemia).
Leaky gut increases inflammation and risk for obesity
Inflammation is directly related to intestinal barrier dysfunction (leaky gut) and it is a hallmark of metabolic syndrome and its related disorders including increased risk for obesity.
One such indicator of leaky gut increasing your risk for obesity is microbiota-derived “lipopolysaccharide (LPS)” . LPS are cell wall components that induce inflammation and can initiate severe systemic effects.
A healthy intestinal lining acts as a barrier that prevents LPS from doing damag. However, a compromised intestinal lining (leaky gut) allows LPS to enter the blood stream where high LPS levels are defined as metabolic endotoxemia
In one mouse study: It was demonstrated that mice with a continuous infusion of LPS over 4 weeks led to increased adipose tissue, fatty liver and increased inflammation and insulin resistance.
5 signs of leaky gut
- Food sensitivities/allergies (wheat/gluten & dairy most common); can try elimination diet for 3 weeks removing a food then challenge it
- Digestive issues: gas, burping, bloating, constipation, diarrhea, abdominal
- Skin issues: eczema, dermatitis, psoriasis
- Nutrient deficiencies: vitamin A, zinc, Vitamin D
- Autoimmune conditions or SIBO (40% + for SIBO after WLS) before sx 15% prevalence
- RA, celiacs, graves, hashimotos, diabetes
Protectors against leaky gut
- Fruits & veggies
- Fermented foods
- Digestive enzymes
- Prebiotic (improve intestinal barrier function)
If you are interested in learning more about leaky gut after weight loss surgery or need help loosing regain. You need to join our Gastric Health Club.
Here is what one of our members has to say:
Your future health awaits…
4:30 Learn what Leaky gut is
6:45 Learn what health conditions are associated with leaky gut
9:20 Learn about Lipopolysaccharides(LPS) and how an elevated level is connected to obesity and diabetes
14:15 Learn what real world things contribute to causing leaky gut
17:00 Learn what research says about WLS and leaky gut
19:00 Learn what signs/symptoms occur when you have leaky gut
23:00 Learn what you can do if you have a leaky gut
Listen, Learn, Enjoy…
References & Links:
- 30 Day Back on Track Program
- Expression of tight-junction proteins in human proximal small intestine mucosa before and after Roux-en-y bypass surgery- Surgery for obesity and related diseases
- Changes in intestinal permeability after Roux-en-Y Gastric Bypass
- Stress and the Gut: Pathophysiology, clinical consequences, diagnostic approach and treatment options
- Is leaky gut syndrome a real condition? An unbiased look
- Could a leaky gut be making you fat?
- Can your gut bacteria help you lose weight?
- Potential mechanisms for the emerging link between obesity and increased intestinal permeability
- Human Intestinal barrier function health and disease
- 10 Signs you have small intestinal bacterial overgrowth(SIBO)
- Probiotics for preventing and treating small intestinal bacterial overgrowth: A meta-analysis and systematic review of current evidence
- Evidence indicates probiotics may help manage SIBO
- GLP-2: A poorly understood mediator enrolled in various bariatric/metabolic surgery-related pathophysiologic mechanisms